Inhibiting citrullination in rheumatoid arthritis: Taking fuel from the fire

Citrullination is a post-translational modification catalysed by peptidylarginine deiminase and is a common feature of inflammation. The presence of anti-citrullinated protein/peptide antibodies (ACPA), however, is unique to rheumatoid arthritis. Several lines of evidence suggest that ACPA are impor...

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Bibliographic Details
Main Authors: Fisher, B, Venables, P
Format: Journal article
Language:English
Published: 2012