A robust mean and variance test with application to high-dimensional phenotypes

Most studies of continuous health-related outcomes examine differences in mean levels (location) of the outcome by exposure. However, identifying effects on the variability (scale) of an outcome, and combining tests of mean and variability (location-and-scale), could provide additional insights into...

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Bibliographic Details
Main Authors: Staley, JR, Windmeijer, F, Suderman, M, Lyon, MS, Davey Smith, G, Tilling, K
Format: Journal article
Language:English
Published: Springer 2021