Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities.

Two large gene and protein superfamilies, SDR and MDR (short- and medium-chain dehydrogenases/reductases), were originally defined from analysis of alcohol and polyol dehydrogenases. The superfamilies contain minimally 82 and 25 genes, respectively, in humans, minimally 324 and 86 enzyme families wh...

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Main Authors: Jörnvall, H, Hedlund, J, Bergman, T, Oppermann, U, Persson, B
格式: Journal article
語言:English
出版: 2010
主題: