Apolipoprotein A-1 is a novel inducer of aggrecan breakdown in cultured articular cartilage

Geahča maid

• INTERLEUKIN 1 INDUCES AGGRECAN DEGRADATION BY HUMAN ARTICULAR CHONDROCYTES THROUGH A TAK1/MKK4/JNK2 PATHWAY WITHOUT INVOLVEMENT OF NFKB
  Dahkki: Ismail, H, et al.
  Almmustuhtton: (2013)
• Sharp injury to articular cartilage activates JNK and NF kappa B and induces expression of inflammatory response genes
  Dahkki: Watt, F, et al.
  Almmustuhtton: (2006)
• Aggrecan breakdown in cartilage induced by proteolytic fragments of fibronectin: implications in osteoarthritis
  Dahkki: Nagase, H
  Almmustuhtton: (2009)
• Fibronectin fragments induce aggrecan degradation in human cartilage and are increased in osteoarthritic cartilage
  Dahkki: Sofat, N, et al.
  Almmustuhtton: (2007)
• Anti-catabolic effect of fibroblast growth factor-2 in human articular cartilage
  Dahkki: Sawaji, Y, et al.
  Almmustuhtton: (2009)