Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions.

The self-assembly of proteins and peptides into polymeric amyloid fibrils is a process that has important implications ranging from the understanding of protein misfolding disorders to the discovery of novel nanobiomaterials. In this study, we probe the stability of fibrils prepared at pH 2.0 and co...

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Bibliographic Details
Main Authors: Shammas, S, Knowles, T, Baldwin, A, Macphee, C, Welland, M, Dobson, C, Devlin, G
Format: Journal article
Language:English
Published: 2011