Glycosylation of immunoglobulin g: role of genetic and epigenetic influences
Objective To determine the extent to which genetic and epigenetic factors contribute to variations in glycosylation of immunoglobulin G (IgG) in humans. Methods 76 N-glycan traits in circulating IgG were analyzed by UPLC in 220 monozygotic and 310 dizygotic twin pairs from TwinsUK. A classical twin...
Главные авторы: | , , , , , , , , , , , , , |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
Public Library of Science
2013
|