T cell microvilli simulations show operation near packing limit and impact on antigen recognition

T cells are immune cells that continuously scan for foreign-derived antigens on the surfaces of nearly all cells, termed antigen-presenting cells (APCs). They do this by dynamically extending numerous protrusions called microvilli (MVs) that contain T cell receptors toward the APC surface in order t...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Morgan, J, Pettmann, J, Dushek, O, Lindsay, AE
Formaat: Journal article
Taal:English
Gepubliceerd in: Cell Press 2022