The roles played by the transcriptional regulators PPARalpha, HIF-1alpha and SIRT1 in the control of cardiac metabolism

<p>The failing heart is characterised by altered energy substrate metabolism, which is a potential target for the development of new heart failure treatments. Transcriptional regulatory proteins orchestrate long-term control of cardiac metabolism by altering gene expression patterns. Thus, the...

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Bibliographic Details
Main Author: Ambrose, L
Other Authors: Carr, C
Format: Thesis
Language:English
Published: 2014
Subjects: