The roles played by the transcriptional regulators PPARalpha, HIF-1alpha and SIRT1 in the control of cardiac metabolism
<p>The failing heart is characterised by altered energy substrate metabolism, which is a potential target for the development of new heart failure treatments. Transcriptional regulatory proteins orchestrate long-term control of cardiac metabolism by altering gene expression patterns. Thus, the...
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Format: | Thesis |
Language: | English |
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2014
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