Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla
Introduction: Lithium remains the most effective treatment for bipolar disorder but tolerance and safety issues complicate its clinical use. The antioxidant drug, ebselen, has been proposed as a possible lithium-mimetic based on its ability in animals to inhibit inositol monophosphatase (IMPase) and...
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Oxford University Press
2016
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