Association between C677T polymorphism of methylene tetrahydrofolate reductase and congenital heart disease: meta-analysis of 7697 cases and 13,125 controls.

BACKGROUND: Association between the C677T polymorphism of the methylene tetrahydrofolate reductase (MTHFR) gene and congenital heart disease (CHD) is contentious. METHODS AND RESULTS: We compared genotypes between CHD cases and controls and between mothers of CHD cases and controls. We placed our re...

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Bibliographic Details
Main Authors: Mamasoula, C, Prentice, R, Pierscionek, T, Pangilinan, F, Mills, J, Druschel, C, Pass, K, Russell, M, Hall, D, Töpf, A, Brown, D, Zelenika, D, Bentham, J, Cosgrove, C, Bhattacharya, S, Riveron, J, Setchfield, K, Brook, J, Bu'Lock, F, Thornborough, C, Rahman, T, Doza, J, Tan, H, O'Sullivan, J, Stuart, A
Format: Journal article
Language:English
Published: 2013