Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation

Platelets harbor the primary reservoir of circulating plasminogen activator inhibitor 1 (PAI-1), but the reportedly low functional activity of this pool of inhibitor has led to debate over its contribution to thrombus stability. Here we analyze the fate of PAI-1 secreted from activated platelets and...

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Bibliographic Details
Main Authors: Morrow, GB, Whyte, CS, Mutch, NJ
Format: Journal article
Language:English
Published: Ferrata Storti Foundation 2019