Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation
Platelets harbor the primary reservoir of circulating plasminogen activator inhibitor 1 (PAI-1), but the reportedly low functional activity of this pool of inhibitor has led to debate over its contribution to thrombus stability. Here we analyze the fate of PAI-1 secreted from activated platelets and...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Ferrata Storti Foundation
2019
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