An investigation into the role of methylation in mammalian X-chromosome inactivation

An investigation into the role of methylation in mammalian X-chromosome inactivation

<p>X-chromosome inactivation achieves dosage compensation of X-linked genes between male (XY) and female (XX) mammals. This process involves the down-regulation of most, but not all genes on one of the two X-chromosomes in the nucleus of each female somatic cell. The mechanism of X-inactivati...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Ian., S, Simpson T. Ian
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	1999
Pynciau:	Gene silencing Molecular aspects X chromosome

Eitemau Tebyg

Genomic regulation and molecular pathways of X chromosome inactivation
gan: Bowness, JS
Cyhoeddwyd: (2021)

A Comparative Analysis of Mouse Imprinted and Random X-Chromosome Inactivation
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Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation
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Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
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Escape From X-Chromosome Inactivation: An Evolutionary Perspective
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Mechanisms for CpG Island Methylation during X chromosome inactivation
gan: Yasmin, K
Cyhoeddwyd: (2024)

An investigation of a hemophilia A female with heterozygous intron 22 inversion and skewed X chromosome inactivation
gan: Xiaoyan Tan, et al.
Cyhoeddwyd: (2025-01-01)

X Chromosome Inactivation in Opioid Addicted Women
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Cyhoeddwyd: (2015-07-01)

Escape from X chromosome inactivation and female bias of autoimmune diseases
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Cyhoeddwyd: (2020-12-01)

Who’s afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
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Cyhoeddwyd: (2023-01-01)

IndiSPENsable for X Chromosome Inactivation and Gene Silencing
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Mechanisms of Choice in X-Chromosome Inactivation
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Ageing-associated changes in DNA methylation in X and Y chromosomes
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Cyhoeddwyd: (2011-07-01)

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Cyhoeddwyd: (2002-01-01)

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Cyhoeddwyd: (2014-08-01)

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gan: Rodrigo Lobato
Cyhoeddwyd: (2021-10-01)

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Cyhoeddwyd: (2017-06-01)

Skewed X-Chromosome Inactivation and Compensatory Upregulation of Escape Genes Precludes Major Clinical Symptoms in a Female With a Large Xq Deletion
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Cyhoeddwyd: (2020-03-01)

Evaluation of X chromosome inactivation in endemic Tunisian pemphigus foliaceus
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Cyhoeddwyd: (2022-12-01)

Breaking rules: the complex relationship between DNA methylation and X-chromosome inactivation in the human placenta
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Cyhoeddwyd: (2025-03-01)

The human inactive X chromosome modulates expression of the active X chromosome
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Cyhoeddwyd: (2023-02-01)

Intelligence Quotient Variability in Klinefelter Syndrome Is Associated With GTPBP6 Expression Under Regulation of X-Chromosome Inactivation Pattern
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Cyhoeddwyd: (2021-09-01)

Localized accumulation of Xist RNA in X chromosome inactivation
gan: Neil Brockdorff
Cyhoeddwyd: (2019-12-01)

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Cyhoeddwyd: (2015-08-01)

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Cyhoeddwyd: (2024-08-01)

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Cyhoeddwyd: (2020-05-01)

The Impact of X-Chromosome Inactivation on Phenotypic Expression of X-Linked Neurodevelopmental Disorders
gan: Boudewien A Brand, et al.
Cyhoeddwyd: (2021-07-01)

Role of Circulating X-Chromosome Inactivation and <i>Xist</i> as Biomarkers in Female Carriers of Fabry Disease
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Cyhoeddwyd: (2024-11-01)

Stochastic gene expression and chromosome interactions in protecting the human active X from silencing by XIST
gan: Barbara R. Migeon
Cyhoeddwyd: (2021-01-01)

X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease
gan: Dan N. Predescu, et al.
Cyhoeddwyd: (2024-12-01)

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Cyhoeddwyd: (2012-07-01)

Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans
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Cyhoeddwyd: (2022-11-01)

Sex differences in number of X chromosomes and X-chromosome inactivation in females promote greater variability in hearing among males
gan: Van Summers
Cyhoeddwyd: (2022-09-01)

A statistical measure for the skewness of X chromosome inactivation based on family trios
gan: Si-Qi Xu, et al.
Cyhoeddwyd: (2018-12-01)

X Inactivation and Escape: Epigenetic and Structural Features
gan: He Fang, et al.
Cyhoeddwyd: (2019-10-01)

Acceleration of X-chromosome gene order evolution in the cattle lineage
gan: Woncheoul Park, et al.
Cyhoeddwyd: (2013-06-01)

Role of loss and skew of X chromosome inactivation for developing myelodysplastic syndrome in patients with Klinefelter syndrome: A brief review of the literature
gan: Masahiro Imamura
Cyhoeddwyd: (2023-01-01)