An investigation into the role of methylation in mammalian X-chromosome inactivation

An investigation into the role of methylation in mammalian X-chromosome inactivation

<p>X-chromosome inactivation achieves dosage compensation of X-linked genes between male (XY) and female (XX) mammals. This process involves the down-regulation of most, but not all genes on one of the two X-chromosomes in the nucleus of each female somatic cell. The mechanism of X-inactivati...

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Bibliografiske detaljer
Main Authors:	Ian., S, Simpson T. Ian
Format:	Thesis
Sprog:	English
Udgivet:	1999
Fag:	Gene silencing Molecular aspects X chromosome

Lignende værker

Genomic regulation and molecular pathways of X chromosome inactivation
af: Bowness, JS
Udgivet: (2021)

A Comparative Analysis of Mouse Imprinted and Random X-Chromosome Inactivation
af: Rebecca M. Malcore, et al.
Udgivet: (2024-02-01)

Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation
af: Irene Talon, et al.
Udgivet: (2019-09-01)

Molecular biology of X-chromosome disease
af: Chen, Z, et al.
Udgivet: (1992)

Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
af: Ikrame Naciri, et al.
Udgivet: (2021-06-01)

X-Chromosome Inactivation and Autosomal Random Monoallelic Expression as “Faux Amis”
af: Vasco M. Barreto, et al.
Udgivet: (2021-09-01)

Escape From X-Chromosome Inactivation: An Evolutionary Perspective
af: Bronwyn J. Posynick, et al.
Udgivet: (2019-10-01)

Mechanisms for CpG Island Methylation during X chromosome inactivation
af: Yasmin, K
Udgivet: (2024)

An investigation of a hemophilia A female with heterozygous intron 22 inversion and skewed X chromosome inactivation
af: Xiaoyan Tan, et al.
Udgivet: (2025-01-01)

X Chromosome Inactivation in Opioid Addicted Women
af: Nasim Vousooghi, et al.
Udgivet: (2015-07-01)

Escape from X chromosome inactivation and female bias of autoimmune diseases
af: Mohammad Javad Mousavi, et al.
Udgivet: (2020-12-01)

Who’s afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
af: Amy M. Inkster, et al.
Udgivet: (2023-01-01)

IndiSPENsable for X Chromosome Inactivation and Gene Silencing
af: Corinne Kaufmann, et al.
Udgivet: (2023-11-01)

Mechanisms of Choice in X-Chromosome Inactivation
af: Giulia Furlan, et al.
Udgivet: (2022-02-01)

Ageing-associated changes in DNA methylation in X and Y chromosomes
af: Laura Kananen, et al.
Udgivet: (2021-07-01)

A History of the Discovery of Random X Chromosome Inactivation in the Human Female and its Significance
af: Sophia Balderman, et al.
Udgivet: (2011-07-01)

Late-replicating X-chromosome: replication patterns in mammalian females
af: Tunin Karen, et al.
Udgivet: (2002-01-01)

X-inactivation normalizes O-GlcNAc Transferase levels and generates an O-GlcNAc-depleted Barr body
af: Stéphanie eOlivier-Van Stichelen, et al.
Udgivet: (2014-08-01)

A quantum mechanical approach to random X chromosome inactivation
af: Rodrigo Lobato
Udgivet: (2021-10-01)

X-autosome and X-Y translocations in female carriers: X-chromosome inactivation easily detectable by 5-ethynyl-2-deoxyuridine (EdU)
af: Donat M, et al.
Udgivet: (2017-06-01)

Skewed X-Chromosome Inactivation and Compensatory Upregulation of Escape Genes Precludes Major Clinical Symptoms in a Female With a Large Xq Deletion
af: Cíntia B. Santos-Rebouças, et al.
Udgivet: (2020-03-01)

Evaluation of X chromosome inactivation in endemic Tunisian pemphigus foliaceus
af: Olfa Abida, et al.
Udgivet: (2022-12-01)

Breaking rules: the complex relationship between DNA methylation and X-chromosome inactivation in the human placenta
af: Amy M Inkster, et al.
Udgivet: (2025-03-01)

The human inactive X chromosome modulates expression of the active X chromosome
af: Adrianna K. San Roman, et al.
Udgivet: (2023-02-01)

Intelligence Quotient Variability in Klinefelter Syndrome Is Associated With GTPBP6 Expression Under Regulation of X-Chromosome Inactivation Pattern
af: Luciane Simonetti, et al.
Udgivet: (2021-09-01)

Localized accumulation of Xist RNA in X chromosome inactivation
af: Neil Brockdorff
Udgivet: (2019-12-01)

Over-expression of XIST, the Master Gene for X Chromosome Inactivation, in Females With Major Affective Disorders
af: Baohu Ji, et al.
Udgivet: (2015-08-01)

Inferring clonal somatic mutations directed by X chromosome inactivation status in single cells
af: Ilke Demirci, et al.
Udgivet: (2024-08-01)

Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation
af: Ava C Carter, et al.
Udgivet: (2020-05-01)

The Impact of X-Chromosome Inactivation on Phenotypic Expression of X-Linked Neurodevelopmental Disorders
af: Boudewien A Brand, et al.
Udgivet: (2021-07-01)

Role of Circulating X-Chromosome Inactivation and <i>Xist</i> as Biomarkers in Female Carriers of Fabry Disease
af: Salvatore Rossi, et al.
Udgivet: (2024-11-01)

Stochastic gene expression and chromosome interactions in protecting the human active X from silencing by XIST
af: Barbara R. Migeon
Udgivet: (2021-01-01)

X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease
af: Dan N. Predescu, et al.
Udgivet: (2024-12-01)

Deep ancestry of mammalian X chromosome revealed by comparison with the basal tetrapod <it>Xenopus tropicalis</it>
af: Mácha Jaroslav, et al.
Udgivet: (2012-07-01)

Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans
af: Amy L Roberts, et al.
Udgivet: (2022-11-01)

Sex differences in number of X chromosomes and X-chromosome inactivation in females promote greater variability in hearing among males
af: Van Summers
Udgivet: (2022-09-01)

A statistical measure for the skewness of X chromosome inactivation based on family trios
af: Si-Qi Xu, et al.
Udgivet: (2018-12-01)

X Inactivation and Escape: Epigenetic and Structural Features
af: He Fang, et al.
Udgivet: (2019-10-01)

Acceleration of X-chromosome gene order evolution in the cattle lineage
af: Woncheoul Park, et al.
Udgivet: (2013-06-01)

Role of loss and skew of X chromosome inactivation for developing myelodysplastic syndrome in patients with Klinefelter syndrome: A brief review of the literature
af: Masahiro Imamura
Udgivet: (2023-01-01)