Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1.

BACKGROUND: Neural cell adhesion molecules of the immunoglobulin superfamily (IgCAMs) have been implicated in both the fasciculation and guidance of axons, but direct genetic evidence of a role for neural IgCAMs in axon guidance in vertebrates is lacking. The L1 subfamily of vertebrate neural IgCAMs...

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Bibliographic Details
Main Authors: Cohen, N, Taylor, J, Scott, L, Guillery, R, Soriano, P, Furley, A
Format: Journal article
Language:English
Published: 1998