Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.

The cytoskeletal protein talin binds to a short C-terminal sequence in phosphatidylinositol phosphate kinase type Igamma (PIPKIgamma), activating the enzyme and promoting the local production of phosphatidylinositol 4,5 bisphosphate, which regulates focal adhesion dynamics as well as clathrin-mediat...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: de Pereda, J, Wegener, K, Santelli, E, Bate, N, Ginsberg, M, Critchley, DR, Campbell, I, Liddington, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2005