A contaminant-free assessment of Endogenous Retroviral RNA in human plasma

Endogenous retroviruses (ERVs) comprise 6-8% of the human genome. HERVs are silenced in most normal tissues, up-regulated in stem cells and in placenta but also in cancer and HIV-1 infection. Crucially, there are conflicting reports on detecting HERV RNA in non-cellular clinical samples such as plas...

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Bibliographic Details
Main Authors: Karamitros, T, Paraskevis, D, Hatzakis, A, Psichogiou, M, Elefsiniotis, I, Hurst, T, Geretti, A, Beloukas, A, Frater, J, Klenerman, P, Katzourakis, A, Magiorkinis, G
Format: Journal article
Language:English
Published: Nature Publishing Group 2016