A contaminant-free assessment of Endogenous Retroviral RNA in human plasma

A contaminant-free assessment of Endogenous Retroviral RNA in human plasma

Endogenous retroviruses (ERVs) comprise 6-8% of the human genome. HERVs are silenced in most normal tissues, up-regulated in stem cells and in placenta but also in cancer and HIV-1 infection. Crucially, there are conflicting reports on detecting HERV RNA in non-cellular clinical samples such as plas...

Full description

Bibliographic Details
Main Authors:	Karamitros, T, Paraskevis, D, Hatzakis, A, Psichogiou, M, Elefsiniotis, I, Hurst, T, Geretti, A, Beloukas, A, Frater, J, Klenerman, P, Katzourakis, A, Magiorkinis, G
Format:	Journal article
Language:	English
Published:	Nature Publishing Group 2016

Similar Items

Assessment of phylogenetic sensitivity for reconstructing HIV-1 epidemiological relationships
by: Beloukas, A, et al.
Published: (2012)

Assessment of phylogenetic sensitivity for reconstructing HIV-1 epidemiological relationships
by: Beloukas, A, et al.
Published: (2012)

Assessment of phylogenetic sensitivity for reconstructing HIV-1 epidemiological relationships.
by: Beloukas, A, et al.
Published: (2012)

Limitations of current high-throughput sequencing technologies lead to biased expression estimates of endogenous retroviral elements
by: Kitsou, K, et al.
Published: (2024)

Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency
by: Hurst, T, et al.
Published: (2016)

Human endogenous retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model
by: Karamitros, T, et al.
Published: (2018)

Sex-specific aspects of endogenous retroviral insertion and deletion.
by: Gemmell, P, et al.
Published: (2013)

The evolution of endogenous retroviral envelope genes in bats and their potential contribution to host biology
by: Skirmuntt, EC, et al.
Published: (2019)

Impact of interferon-alpha receptor-1 promoter polymorphisms on the transcriptome of the hepatitis B virus-associated hepatocellular carcinoma
by: Karamitros, T, et al.
Published: (2018)

Reducing HIV infection in people who inject drugs is impossible without targeting recently-infected subjects
by: Vasylyeva, T, et al.
Published: (2016)

Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular Carcinoma
by: Timokratis Karamitros, et al.
Published: (2018-04-01)

Interferon-inducible protein 16 (IFI16) has a broad-spectrum binding ability against ssDNA targets: An evolutionary hypothesis for antiretroviral checkpoint
by: Hurst, T, et al.
Published: (2019)

Larger mammalian body size leads to lower retroviral activity
by: Katzourakis, A, et al.
Published: (2014)

Roles of endogenous retroviruses in early life events
by: Magiorkinis, G, et al.
Published: (2017)

Re-analysis of a human hepatitis B virus (HBV) isolate from an East African wild born Pan troglodytes schweinfurthii: evidence for interspecies recombination between HBV infecting chimpanzee and human.
by: Magiorkinis, E, et al.
Published: (2005)

Comments on "the distribution of HIV-1 recombination breakpoints" by Jun Fan, Matteo Negroni, David L. Robertson.
by: Magiorkinis, G, et al.
Published: (2008)

BreakAlign: a Perl program to align chimaeric (split) genomic NGS reads and allow visual confirmation of novel retroviral integrations
by: Emanuele Marchi, et al.
Published: (2022-04-01)

Re-analysis of 34 full-length HIV-1 intersubtype recombinant sequences
by: Magiorkinis, G, et al.
Published: (2005)

Reanalysis of the HIV-1 circulating recombinant form A/E (CRF01_AE): evidence of A/E/G recombination.
by: Magiorkinis, G, et al.
Published: (2002)

Re-analysis of 34 full-length HIV-1 intersubtype recombinant sequences.
by: Magiorkinis, G, et al.
Published: (2005)

'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era.
by: Magiorkinis, G, et al.
Published: (2013)

'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era.
by: Magiorkinis, G, et al.
Published: (2013)

An innovative study design to assess the community effect of interventions to mitigate HIV epidemics using transmission-chain phylodynamics
by: Magiorkinis, G, et al.
Published: (2018)

The interferon receptor-1 promoter polymorphisms affect the outcome of Caucasians with HBeAg-negative chronic HBV infection
by: Karamitros, T, et al.
Published: (2015)

Analysing the evolutionary history of HCV: puzzle of ancient phylogenetic discordance.
by: Magiorkinis, G, et al.
Published: (2007)

Larger mammalian body size leads to lower retroviral activity.
by: Aris Katzourakis, et al.
Published: (2014-07-01)

Convergent capture of retroviral superantigens by mammalian herpesviruses
by: Aswad, A, et al.
Published: (2015)

Activation of the innate immune response by endogenous retroviruses.
by: Hurst, T, et al.
Published: (2015)

The phylogenetic information profile of HIV-1 and the degradation effect of recombination.
by: Magiorkinis, G, et al.
Published: (2008)

Quantitative detection of the M204V hepatitis B virus minor variants by amplification refractory mutation system real-time PCR combined with molecular beacon technology.
by: Ntziora, F, et al.
Published: (2009)

In vivo characteristics of human immunodeficiency virus type 1 intersubtype recombination: determination of hot spots and correlation with sequence similarity.
by: Magiorkinis, G, et al.
Published: (2003)

Interferon-Inducible Protein 16 (IFI16) Has a Broad-Spectrum Binding Ability Against ssDNA Targets: An Evolutionary Hypothesis for Antiretroviral Checkpoint
by: Tara Patricia Hurst, et al.
Published: (2019-07-01)

Env-less endogenous retroviruses are genomic superspreaders.
by: Magiorkinis, G, et al.
Published: (2012)

Reducing HIV infection in people who inject drugs is impossible without targeting recently-infected subjects.
by: Vasylyeva, TI, et al.
Published: (2016)

Epigenetic Control of Human Endogenous Retrovirus Expression: focus on regulation of long-terminal repeats (LTRs)
by: Hurst, T, et al.
Published: (2017)

Widespread endogenization of genome sequences of non-retroviral RNA viruses into plant genomes.
by: Sotaro Chiba, et al.
Published: (2011-07-01)

Dating the origin and dispersal of hepatitis B virus infection in humans and primates.
by: Paraskevis, D, et al.
Published: (2013)

Dating the origin and dispersal of hepatitis B virus infection in humans and primates
by: Paraskevis, D, et al.
Published: (2013)

The impact of primary prevention and treatment as prevention in controlling the epidemic of hepatitis C under the new therapeutic options
by: Sypsa, V, et al.
Published: (2012)

Endogenous retroviral solo-LTRs in human genome
by: Mingyue Chen, et al.
Published: (2024-03-01)