Receptor concentration and diffusivity control multivalent binding of Sv40 to membrane bilayers

Incoming Simian Virus 40 particles bind to their cellular receptor, the glycolipid GM1, in the plasma membrane and thereby induce membrane deformation beneath the virion leading to endocytosis and infection. Efficient membrane deformation depends on receptor lipid structure and the organization of b...

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Bibliographic Details
Main Authors: Szklarczyk, O, González-Segredo, N, Kukura, P, Oppenheim, A, Choquet, D, Sandoghdar, V, Helenius, A, Sbalzarini, I, Ewers, H
Format: Journal article
Language:English
Published: Public Library of Science 2013