Modulation of the hyperpolarization-activated current (I(f)) by calcium and calmodulin in the guinea-pig sino-atrial node.

The aim of this study was to investigate possible regulation of the hyperpolarization-activated current (I(f)) by cytosolic calcium in guinea-pig sino-atrial (SA) node cells. Isolated SA node cells were superfused with physiological saline solution (36 degrees C) and the perforated patch voltage-cla...

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Bibliographic Details
Main Authors: Rigg, L, Mattick, P, Heath, B, Terrar, D
Format: Journal article
Language:English
Published: 2003