A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect.

In a recent article, a candidate pathway approach was taken to try to identify single nucleotide polymorphisms (SNP) that make up the genetic variation, which underlies the phenotypic variation seen between individuals in their susceptibility to cancer and the progression of their disease. The p53 s...

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Autori principali: Bond, G, Hu, W, Levine, A
Natura: Journal article
Lingua:English
Pubblicazione: 2005