Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation

Brain injury elicits a systemic acute-phase response (APR), which is responsible for co-ordinating the peripheral immunological response to injury. To date, the mechanisms responsible for signalling the presence of injury or disease to selectively activate responses in distant organs were unclear. C...

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Bibliographic Details
Main Authors: Couch, Y, Akbar, N, Roodselaar, J, Evans, M, Gardiner, C, Sargent, I, Romero, I, Bristow, A, Buchan, A, Haughey, N, Anthony, D
Format: Journal article
Published: Springer Nature 2017