Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation
Brain injury elicits a systemic acute-phase response (APR), which is responsible for co-ordinating the peripheral immunological response to injury. To date, the mechanisms responsible for signalling the presence of injury or disease to selectively activate responses in distant organs were unclear. C...
Main Authors: | Couch, Y, Akbar, N, Roodselaar, J, Evans, M, Gardiner, C, Sargent, I, Romero, I, Bristow, A, Buchan, A, Haughey, N, Anthony, D |
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Format: | Journal article |
Published: |
Springer Nature
2017
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