Novel chiral skeletons for drug discovery: antibacterial tetramic acids.

Modification of the ring nucleus of tetramic acids derived from serine gives chiral heterocyclic libraries that exhibit antibacterial activity, and correlation with various physicochemical parameters indicates that chiral tetramic acids may provide a potentially valuable non-aromatic skeleton for fr...

Cijeli opis

Bibliografski detalji
Glavni autori: Holloway, C, Matthews, C, Jeong, Y, Moloney, M, Roberts, C, Yaqoob, M
Format: Journal article
Jezik:English
Izdano: 2011