Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Organisms obtain creatine from their diet or by de novo synthesis via AGAT (L-arginine:glycine amidinotransferase) and GAMT (Guanidinoacetate N-methyltrasferase) in kidney and liver, respectively. AGAT also synthesizes homoarginine (hArg), low levels of which predict poor outcomes in human cardiovas...

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Autors principals:	Lygate, CA, Lake, HA, McAndrew, DJ, Neubauer, S, Zervou, S
Format:	Journal article
Idioma:	English
Publicat:	Frontiers Media 2022

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