Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
Organisms obtain creatine from their diet or by de novo synthesis via AGAT (L-arginine:glycine amidinotransferase) and GAMT (Guanidinoacetate N-methyltrasferase) in kidney and liver, respectively. AGAT also synthesizes homoarginine (hArg), low levels of which predict poor outcomes in human cardiovas...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Frontiers Media
2022
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