Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Organisms obtain creatine from their diet or by de novo synthesis via AGAT (L-arginine:glycine amidinotransferase) and GAMT (Guanidinoacetate N-methyltrasferase) in kidney and liver, respectively. AGAT also synthesizes homoarginine (hArg), low levels of which predict poor outcomes in human cardiovas...

Podrobná bibliografie
Hlavní autoři:	Lygate, CA, Lake, HA, McAndrew, DJ, Neubauer, S, Zervou, S
Médium:	Journal article
Jazyk:	English
Vydáno:	Frontiers Media 2022

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