Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse

Organisms obtain creatine from their diet or by de novo synthesis via AGAT (L-arginine:glycine amidinotransferase) and GAMT (Guanidinoacetate N-methyltrasferase) in kidney and liver, respectively. AGAT also synthesizes homoarginine (hArg), low levels of which predict poor outcomes in human cardiovas...

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Bibliographische Detailangaben
Hauptverfasser:	Lygate, CA, Lake, HA, McAndrew, DJ, Neubauer, S, Zervou, S
Format:	Journal article
Sprache:	English
Veröffentlicht:	Frontiers Media 2022

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