Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling.

Ca(2+) signaling regulates cell function. This is subject to modulation by H(+) ions that are universal end-products of metabolism. Due to slow diffusion and common buffers, changes in cytoplasmic [Ca(2+)] ([Ca(2+)]i) or [H(+)] ([H(+)]i) can become compartmentalized, leading potentially to complex s...

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Bibliographic Details
Main Authors: Swietach, P, Youm, J, Saegusa, N, Leem, C, Spitzer, K, Vaughan-Jones, R
Format: Journal article
Language:English
Published: 2013