CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76?

T cells require dual stimulation to become activated. When T cells encounter antigen-presenting cells, both the T cell receptor (TCR) and the CD28 coreceptor are ligated and activated. Michel and Acuto discuss how the adaptor SLP-76, which is recruited to the activated TCR complex, and the Rho famil...

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Bibliografski detalji
Glavni autori: Michel, F, Acuto, O
Format: Journal article
Jezik:English
Izdano: 2002