A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa.

The rd1 natural mutant is one of the first and probably the most commonly studied mouse model for retinitis pigmentosa (RP), a severe and frequently blinding human retinal degeneration. In several decades of research, the link between the increase in photoreceptor cGMP levels and the extremely rapid...

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Bibliographic Details
Main Authors: Paquet-Durand, F, Beck, S, Michalakis, S, Goldmann, T, Huber, G, Mühlfriedel, R, Trifunović, D, Fischer, M, Fahl, E, Duetsch, G, Becirovic, E, Wolfrum, U, van Veen, T, Biel, M, Tanimoto, N, Seeliger, M
Format: Journal article
Language:English
Published: 2011