Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.
Nearly all human genetic disorders result from a limited repertoire of mutations in an associated gene or its regulatory elements. We recently described an individual with an inherited form of anemia (alpha-thalassemia) who has a deletion that results in a truncated, widely expressed gene (LUC7L) be...
| Glavni autori: | , , , , , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2003
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