Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.

Nearly all human genetic disorders result from a limited repertoire of mutations in an associated gene or its regulatory elements. We recently described an individual with an inherited form of anemia (alpha-thalassemia) who has a deletion that results in a truncated, widely expressed gene (LUC7L) be...

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Bibliográfalaš dieđut
Váldodahkkit: Tufarelli, C, Stanley, J, Garrick, D, Sharpe, J, Ayyub, H, Wood, W, Higgs, D
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2003