The interplay between JNK pathway activation, proteoglycan turnover and endocytosis in chondrocytes
The JNK pathway (c-jun N-terminal kinase) is activated by a variety of inflammatory and physical stressful stimuli. Recently, we identified a new and an important role for the JNK pathway in the turnover of the cartilage proteoglycan aggrecan. Loss of JNK2 isoform in human chondrocytes and murine ca...
| Main Authors: | , , , , , |
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| Format: | Conference item |
| Published: |
Wiley
2017
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