Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma.

Hypoxia and pH influence gene expression in tumours, and it is becoming increasingly clear that the pattern of genes expressed by a tumour determines its growth and survival characteristics. Hypoxia-inducible factor-1 (HIF-1) is a key mediator of the cellular response to hypoxia and high HIF-1 expre...

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Bibliographic Details
Main Authors: Watson, P, Chia, S, Wykoff, C, Han, C, Leek, R, Sly, W, Gatter, K, Ratcliffe, P, Harris, A
Format: Journal article
Language:English
Published: 2003