Developing genome-editing strategies to ameliorate HbE/beta-thalassaemia
<p>The thalassaemias are the most common monogenic disorders worldwide. Both α- and β-thalassaemia are caused by genetic mutations that result in a decrease in globin gene expression and protein synthesis. The more clinically significant of the two disorders, β-thalassaemia is mainly caused by...
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| Format: | Thesis |
| Language: | English |
| Published: |
2021
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