Developing genome-editing strategies to ameliorate HbE/beta-thalassaemia

<p>The thalassaemias are the most common monogenic disorders worldwide. Both α- and β-thalassaemia are caused by genetic mutations that result in a decrease in globin gene expression and protein synthesis. The more clinically significant of the two disorders, β-thalassaemia is mainly caused by...

Повний опис

Бібліографічні деталі
Автор: Badat, M
Інші автори: Higgs, D
Формат: Дисертація
Мова:English
Опубліковано: 2021

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