Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes

The trypanosome genome is characterized by RNA polymerase II-driven polycistronic transcription of protein-coding genes. Ten to hundreds of genes are co-transcribed from a single promoter; thus, selective regulation of individual genes via initiation is impossible. However, selective responses to ex...

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Bibliographic Details
Main Authors: Kelly, S, Kramer, S, Schwede, A, Maini, P, Gull, K, Carrington, M
Format: Journal article
Language:English
Published: Royal Society 2012