Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank

Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank

<p>We aimed to identify potential novel predictors for breast cancer among post-menopausal women, with pre-specified interest in the role of polygenic risk scores (PRS) for risk prediction. We utilised an analysis pipeline where machine learning was used for feature selection, prior to risk pr...

書誌詳細
主要な著者:	Liu, X, Morelli, D, Littlejohns, TJ, Clifton, DA, Clifton, L
フォーマット:	Journal article
言語:	English
出版事項:	Springer Nature 2023

類似資料

Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank
著者:: Xiaonan Liu, 等
出版事項: (2023-06-01)

Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank.
著者:: Yeh, T-S, 等
出版事項: (2023)

Speech‐in‐noise hearing impairment is associated with an increased risk of incident dementia in 82,039 UK Biobank participants
著者:: Stevenson, JS, 等
出版事項: (2021)

Assessing agreement between different polygenic risk scores in the UK Biobank
著者:: Clifton, LEI, 等
出版事項: (2022)

Assessing the importance of primary care diagnoses in the UK Biobank.
著者:: Clifton, L, 等
出版事項: (2024)

Endogenous hormones and risk of invasive breast cancer in pre- and post-menopausal women: findings from the UK Biobank
著者:: Tin Tin, S, 等
出版事項: (2021)

Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank
著者:: Tian-Shin Yeh, 等
出版事項: (2023-08-01)

Association between metabolic syndrome and risk of incident dementia in UK Biobank
著者:: Qureshi, D, 等
出版事項: (2023)

Assessing agreement between different polygenic risk scores in the UK Biobank
著者:: Lei Clifton, 等
出版事項: (2022-07-01)

Calculating polygenic risk scores (PRS) in UK Biobank: A practical guide for epidemiologists
著者:: Collister, JA, 等
出版事項: (2022)

Human cytomegalovirus and risk of incident cardiovascular disease in United Kingdom Biobank
著者:: Hamilton, EM, 等
出版事項: (2022)

UK Biobank: Opportunities for cardiovascular research
著者:: Littlejohns, T, 等
出版事項: (2017)

Independent external validation of the QRISK3 cardiovascular disease risk prediction model using UK Biobank
著者:: Parsons, RE, 等
出版事項: (2023)

Clinical prediction models in epidemiological studies: lessons from the application of QRISK3 to UK Biobank Data
著者:: Parsons, RE, 等
出版事項: (2022)

Polygenic risk of prediabetes, undiagnosed diabetes, and incident type 2 diabetes stratified by diabetes risk factors
著者:: Liu, X, 等
出版事項: (2023)

United Kingdom Biobank (UK Biobank): JACC Focus Seminar 6/8
著者:: Caleyachetty, R, 等
出版事項: (2021)

Association of metabolic syndrome with neuroimaging and cognitive outcomes in the UK Biobank
著者:: Qureshi, D, 等
出版事項: (2024)

Fluid intake and dietary factors and the risk of incident kidney stones in UK biobank: a population-based prospective cohort study
著者:: Littlejohns, T, 等
出版事項: (2019)

Genetic predictors of participation in optional components of UK Biobank
著者:: Jessica Tyrrell, 等
出版事項: (2021-02-01)

Accuracy of identifying incident stroke cases from linked health care data in UK Biobank
著者:: Rannikmäe, K, 等
出版事項: (2020)

Identifying top ten predictors of type 2 diabetes through machine learning analysis of UK Biobank data
著者:: Moa Lugner, 等
出版事項: (2024-01-01)

Physical activity and breast cancer risk: results from the UK Biobank prospective cohort
著者:: Guo, W, 等
出版事項: (2020)

Association between coeliac disease and cardiovascular disease: a prospective analysis in UK Biobank
著者:: Conroy, M, 等
出版事項: (2023)

Lifestyle factors and prostate-specific antigen (PSA) testing in UK Biobank: Implications for epidemiological research
著者:: Littlejohns, T, 等
出版事項: (2016)

The advantages of UK Biobank's open‐access strategy for health research
著者:: Conroy, M, 等
出版事項: (2019)

Algorithms for the capture and adjudication of prevalent and incident diabetes in UK Biobank
著者:: Eastwood, S, 等
出版事項: (2016)

Women’s reproductive factors and incident cardiovascular disease in the UK Biobank
著者:: Peters, SAE, 等
出版事項: (2018)

Algorithms for the Capture and Adjudication of Prevalent and Incident Diabetes in UK Biobank.
著者:: Sophie V Eastwood, 等
出版事項: (2016-01-01)

Examination of potential novel biochemical factors in relation to prostate cancer incidence and mortality in UK Biobank
著者:: Perez-Cornago, A, 等
出版事項: (2020)

Association between coeliac disease and cardiovascular disease: prospective analysis of UK Biobank data
著者:: Elizabeth Soilleux, 等
出版事項: (2023-07-01)

Hypertension, a dementia polygenic risk score, APOE genotype and incident dementia
著者:: Littlejohns, T, 等
出版事項: (2022)

Body size and composition, physical activity and sedentary time in relation to endogenous hormones in pre- and post-menopausal women: findings from the UK Biobank
著者:: Tin Tin, S, 等
出版事項: (2020)

Comparison of sociodemographic and health-related characteristics of UK Biobank participants with the general population
著者:: Fry, A, 等
出版事項: (2017)

BODY WEIGHT, LIPOPROTEIN (A), AND INCIDENT CARDIOVASCULAR DISEASE IN THE UK BIOBANK
著者:: Richard Kazibwe, MD, MS
出版事項: (2024-09-01)

Variations in sex differences in major cardiometabolic risk factors by age and menopause status: results from the UK Biobank
著者:: Mark Woodward, 等
出版事項: (2025-03-01)

Identifying predictive motor factors for falls in post-menopausal breast cancer survivors.
著者:: Marek Zak, 等
出版事項: (2017-01-01)

Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank
著者:: Tiago Azevedo, 等
出版事項: (2023-07-01)

The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study
著者:: Sanghvi, MM, 等
出版事項: (2018)

The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study.
著者:: Mihir M Sanghvi, 等
出版事項: (2018-01-01)

Association between constipation and incident chronic kidney disease in the UK Biobank study
著者:: Kipyo Kim, 等
出版事項: (2024-12-01)