X-ray studies on the mechanism of IPNS using substrate analogs
The substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate...
Κύριοι συγγραφείς: | Long, A, Clifton, I, Roach, P, Schofield, C, Baldwin, J, Hajdu, J |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1997
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies.
ανά: Roach, P, κ.ά.
Έκδοση: (1996) -
Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans.
ανά: Roach, P, κ.ά.
Έκδοση: (1995) -
Anaerobic crystallisation of an isopenicillin N synthase center dot Fe(II)center dot substrate complex demonstrated by X-ray studies
ανά: Roach, P, κ.ά.
Έκδοση: (1996) -
Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
ανά: Roach, P, κ.ά.
Έκδοση: (1997) -
Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate.
ανά: Long, A, κ.ά.
Έκδοση: (2003)