X-ray studies on the mechanism of IPNS using substrate analogs
The substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate...
| Huvudupphovsmän: | , , , , , |
|---|---|
| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
1997
|