Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells.

Invasive Staphylococcus aureus infection frequently involves bacterial seeding from the bloodstream to other body tissues, a process necessarily involving interactions between circulating bacteria and vascular endothelial cells. Staphylococcus aureus fibronectin-binding protein is central to the inv...

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Bibliographic Details
Main Authors: Massey, R, Kantzanou, M, Fowler, T, Day, N, Schofield, K, Wann, E, Berendt, A, Höök, M, Peacock, S
Format: Journal article
Language:English
Published: 2001