Immune responses in the absence of costimulation: viruses know the trick.

Costimulatory molecules are crucial for the induction of immune responses after immunization with purified proteins or peptides. However, some viruses and other pathogens are able to induce protective immunity in the absence of such molecules. This review argues that patterns recognized by both the...

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Bibliographic Details
Main Authors: Bachmann, M, Zinkernagel, R, Oxenius, A
Format: Journal article
Language:English
Published: 1998