SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction
The SARS-CoV-2 receptor, ACE2, is found on pericytes, contractile cells enwrapping capillaries that regulate brain, heart and kidney blood flow. ACE2 converts vasoconstricting angiotensin II into vasodilating angiotensin-(1-7). In brain slices from hamster, which has an ACE2 sequence similar to huma...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2022
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