Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis.

OBJECTIVE: There is a pressing need to develop reliable molecular biomarkers in osteoarthritis. The aim of the study was to identify novel serum biomarkers for osteoarthritis using a metabolomics approach. METHODS: A two-stage study design was utilised. 123 knee osteoarthritis cases and 299 controls...

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Bibliographic Details
Main Authors: Zhai, G, Wang-Sattler, R, Hart, D, Arden, N, Hakim, A, Illig, T, Spector, T
Format: Journal article
Language:English
Published: 2010