Fine-scale mapping of the FGFR2 breast cancer risk locus: Putative functional variants differentially bind FOXA1 and E2F1

Fine-scale mapping of the FGFR2 breast cancer risk locus: Putative functional variants differentially bind FOXA1 and E2F1

Mostrar otras versiones (1)

The 10q26 locus in the second intron of FGFR2 is the locus most strongly associated with estrogen-receptor-positive breast cancer in genome-wide association studies. We conducted fine-scale mapping in case-control studies genotyped with a custom chip (iCOGS), comprising 41 studies (n = 89,050) of Eu...

Descripción completa

Detalles Bibliográficos
Autores principales: Meyer, K, O'Reilly, M, Michailidou, K, Carlebur, S, Edwards, S, French, J, Prathalingham, R, Dennis, J, Bolla, M, Wang, Q, De Santiago, I, Hopper, J, Tsimiklis, H, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Hogervorst, F, Muir, K, Lophatananon, A, Stewart-Brown, S
Formato: Journal article
Publicado: 2013

Ejemplares similares