The population genetics and dynamics of the thalassemias.
The inherited disorders of hemoglobin, including the thalassemias, are by far the commonest monogenic diseases. Although several factors are responsible for their very high frequency, the major mechanism seems to be natural selection mediated by heterozygote protection against severe forms of malari...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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