Costimulation blockade: current perspectives and implications for therapy.
T cells must be activated before they can elicit damage to allografts, through interaction of their T cell receptor (TCR) with peptide-MHC complex and through accessory molecules. Signaling through accessory molecules or costimulatory molecules is a critical way for the immune system to fine tune T...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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