Costimulation blockade: current perspectives and implications for therapy.

T cells must be activated before they can elicit damage to allografts, through interaction of their T cell receptor (TCR) with peptide-MHC complex and through accessory molecules. Signaling through accessory molecules or costimulatory molecules is a critical way for the immune system to fine tune T...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Kinnear, G, Jones, N, Wood, K
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2013