Metabolic gatekeeper function of B-lymphoid transcription factors

B-lymphoid transcription factors, such as PAX5 and IKZF1, are critical for early B-cell development, yet lesions of the genes encoding these transcription factors occur in over 80% of cases of pre-B-cell acute lymphoblastic leukaemia (ALL). The importance of these lesions in ALL has, until now, rema...

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Main Authors:	Chan, LN, Chen, Z, Braas, D, Lee, J-W, Xiao, G, Geng, H, Cosgun, KN, Hurtz, C, Shojaee, S, Cazzaniga, V, Schjerven, H, Ernst, T, Hochhaus, A, Kornblau, SM, Konopleva, M, Pufall, MA, Cazzaniga, G, Liu, GJ, Milne, TA, Koeffler, HP, Ross, TS, Sánchez-García, I, Borkhardt, A, Yamamoto, KR, Dickins, RA, Graeber, TG, Müschen, M
Format:	Journal article
Language:	English
Published:	Springer Nature 2017

Metabolic gatekeeper function of B-lymphoid transcription factors

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