Structural and functional characterization of Falcipain-2, a hemoglobinase from the malarial parasite Plasmodium falciparum.

Malaria is caused by protozoan erythrocytic parasites of the Plasmodium genus, with Plasmodium falciparum being the most dangerous and widespread disease-causing species. Falcipain-2 (FP-2) of P. falciparum is a papain-family (C1A) cysteine protease that plays an important role in the parasite life...

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Bibliographic Details
Main Authors: Hogg, T, Nagarajan, K, Herzberg, S, Chen, L, Shen, X, Jiang, H, Wecke, M, Blohmke, C, Hilgenfeld, R, Schmidt, C
Format: Journal article
Language:English
Published: 2006