A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

This large multi-center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi-modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients with psychosis, 822 unaffected first-degree relatives of patients, and 2,333 c...

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Main Authors: Ranlund, S, Calafato, S, Thygesen, JH, Lin, K, Cahn, W, Crespo-Facorro, B, De Zwarte, SMC, Díez, Á, Di Forti, M, Group, Iyegbe, C, Jablensky, A, Jones, R, Hall, M-H, Kahn, R, Kalaydjieva, L, Kravariti, E, McDonald, C, McIntosh, AM, McQuillin, A, Peic, Picchioni, M, Prata, DP, Rujescu, D, Schulze, K, Shaikh, M, Toulopoulou, T, Van Haren, N, Van Os, J, Vassos, E, Walshe, M, Wtccc2, Lewis, C, Murray, RM, Powell, J, Bramon, E
Format: Journal article
Language:English
Published: Wiley 2017

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